There’s something wonderfully comforting about a Cheesy Loaded Meatloaf Casserole. Picture this: a hearty, cheesy blend of flavors bubbling away in your oven, filling your kitchen with mouthwatering aromas. This dish is a delightful twist on classic meatloaf, and it’s sure to become a favorite in your household. Whether you’re hosting a family dinner or just craving something satisfying, this cheesy meatloaf casserole is your answer.
Why This Dish Matters
This Cheesy Meatloaf Casserole holds a special place in my heart. Growing up, my family often gathered around a comforting meatloaf dinner, and this recipe takes that nostalgia and turns it into a delightful casserole. It’s not just about taste; it’s about memories. Plus, it’s incredibly versatile, it can be dressed up with your favorite veggies or made into a quick weeknight meal. Trust me, once you bring this dish to your table, it won’t just be a meal; it’ll be a recurring joy in your cooking rotation.
Ingredients
- 1 ½ pounds ground beef
- 1 cup breadcrumbs
- 1 cup shredded cheddar cheese
- 1 cup milk
- 1 large egg
- 1 onion, diced
- 2 cloves garlic, minced
- 1 teaspoon salt
- 1 teaspoon black pepper
- 1 tablespoon Worcestershire sauce
- 1 cup ketchup for topping
- Optional: diced bell peppers or mushrooms for added flavor
Instructions
Step 1:
Preheat your oven to 350°F (175°C).
Step 2:
In a large mixing bowl, combine the ground beef, breadcrumbs, shredded cheese, milk, egg, diced onion, minced garlic, salt, black pepper, and Worcestershire sauce.
Step 3:
Mix everything together until fully combined. A fork or your hands work great for this, just make sure not to overmix.
Step 4:
Transfer the meat mixture into a greased casserole dish and shape it into a loaf.
Step 5:
Spread the ketchup evenly over the top of the meatloaf for that classic touch.
Step 6:
Bake in the preheated oven for about 1 hour, or until the meatloaf is cooked through and reaches an internal temperature of 160°F (70°C).
Step 7:
Once done, allow it to rest for a few minutes before slicing. Serve warm and enjoy.

Nutritional Information
This Cheesy Meatloaf Casserole is not only delicious but also hearty. With the combination of protein from the ground beef, the calming carbs from the breadcrumbs, and the richness of cheese, one serving provides a satisfying balance of nutrients.
Healthier Alternatives
If you’re looking to lighten up the recipe, consider swapping out ground beef for ground turkey or chicken. You can also use whole-grain breadcrumbs or reduce the cheese for a lower-calorie dish. You can even add extra veggies like shredded carrots or zucchini to boost the nutritional content without losing flavor.
Serving Suggestions
For a complete meal, serve this casserole alongside a fresh garden salad or some roasted vegetables. If you’re in the mood for something even more comforting, pair it with a side of cheesy garlic butter corn delight; trust me, it’s a wonderful combination. You can find that recipe here.
Common Mistakes
One of the most common mistakes I see is overmixing the meat mixture. You want it to be well combined, but overmixing can make the meatloaf dense. Also, make sure to let it rest before slicing. This helps keep the juices in, making every bite succulent.
Storing Tips
- Store any leftovers in an airtight container in the refrigerator for up to 4 days.
- This casserole also freezes well. Just wrap it tightly and it will be good for about 3 months.
- To reheat, simply thaw overnight in the fridge, then warm it in the oven until heated through.
FAQs
- Q1: Can I make this recipe ahead of time?
A1: Absolutely; You can prepare it a day in advance and just pop it into the oven when you’re ready to bake. - Q2: What can I substitute for breadcrumbs?
A2: You can use crushed crackers or oats as a great alternative. - Q3: How can I make this dish gluten-free?
A3: Use gluten-free breadcrumbs or oats for a similar texture without gluten.
This Cheesy Loaded Meatloaf Casserole is a great way to bring comfort food to the family table. I hope you enjoy making this dish as much as I do. And if you’re looking for another fantastic casserole option, be sure to check out my Cheesy Hamburger Rice Casserole here. Happy cooking.
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Cheesy Loaded Meatloaf Casserole
- Total Time: 1 hour 15 minutes
- Yield: 6 servings 1x
Description
Comfort food at its finest! This Cheesy Loaded Meatloaf Casserole blends hearty, savory meatloaf with gooey cheddar cheese and a tangy ketchup topping, perfect for family dinners or when you’re craving a delicious twist on a classic favorite.
Ingredients
- 1 ½ pounds ground beef
- 1 cup breadcrumbs
- 1 cup shredded cheddar cheese
- 1 cup milk
- 1 large egg
- 1 onion, diced
- 2 cloves garlic, minced
- 1 teaspoon salt
- 1 teaspoon black pepper
- 1 tablespoon Worcestershire sauce
- 1 cup ketchup (for topping)
- Optional: diced bell peppers or mushrooms
Instructions
- Preheat oven to 350°F (175°C).
- In a large bowl, mix ground beef, breadcrumbs, cheese, milk, egg, onion, garlic, salt, pepper, and Worcestershire sauce.
- Gently combine the ingredients without overmixing.
- Place the meat mixture into a greased casserole dish and shape it into a loaf form.
- Spread ketchup evenly over the top of the loaf.
- Bake for approximately 1 hour, or until internal temperature reaches 160°F (70°C).
- Let rest a few minutes before slicing. Serve warm and enjoy!
Notes
Avoid overmixing the meat mixture to keep the texture tender. Let the casserole rest before serving so the juices redistribute for maximum flavor.
- Prep Time: 15 minutes
- Cook Time: 60 minutes
- Category: Main Course
- Method: Baked
- Cuisine: American
Nutrition
- Serving Size: 1 slice
- Calories: 480
- Sugar: 6g
- Sodium: 720mg
- Fat: 32g
- Saturated Fat: 14g
- Unsaturated Fat: 15g
- Trans Fat: 1g
- Carbohydrates: 12g
- Fiber: 1g
- Protein: 32g
- Cholesterol: 110mg
Keywords: meatloaf, casserole, cheesy meatloaf, comfort food